Insulin (resistance)

Insulin resistance syndrome: options for treatment.
[9932820] South Med J 92(1): 2-15 (1999)

The deadly quartet--the insulin resistance syndrome.
[9404899] South Med J 90(12): 1162-8 (1997)

Molecular mechanisms of inherited insulin resistance.
[9349447] QJM 90(9): 557-62 (1997)

Saturated fatty acids and insulin resistance.
[19763019] J Med Invest 56(3-4): 88-92 (2009)

Molecular genetics of severe insulin resistance.
[2697987] Yale J Biol Med 62(5): 533-47 (1989)

Insulin resistance: a potential new target for therapy in patients with heart failure.
[18786090] Cardiovasc Ther 26(3): 203-13 (2008)

Insulin resistance as a membrane microdomain disorder.
[16880599] Biol Pharm Bull 29(8): 1532-7 (2006)

An overview of pathophysiology and treatment of insulin resistance.
[11211569] Indian J Physiol Pharmacol 45(1): 22-36 (2001)

Insulin resistance: a proinflammatory state mediated by lipid-induced signaling dysfunction and involved in atherosclerotic plaque instability.
[18604303] Mediators Inflamm 2008(-): 767623 (2008)

Insulin resistance and non-insulin-dependent diabetes mellitus: cellular and molecular mechanisms.
[7900697] Am J Clin Nutr 61(4 Suppl): 980S-986S (1995)

Insulin resistance in polycystic ovary syndrome: progress and paradoxes.
[11237218] Recent Prog Horm Res 56(-): 295-308 (2001)

Insulin resistance and its treatment by thiazolidinediones.
[11237217] Recent Prog Horm Res 56(-): 265-94 (2001)

Molecular mechanism of insulin resistance.
[17435330] J Biosci 32(2): 405-13 (2007)

Spectrum of renal diseases associated with extreme forms of insulin resistance.
[17699267] Clin J Am Soc Nephrol 1(4): 616-22 (2006)

Cross-talk between GlcNAcylation and phosphorylation: roles in insulin resistance and glucose toxicity.
[18445751] Am J Physiol Endocrinol Metab 295(1): E17-28 (2008)

Current approaches for assessing insulin sensitivity and resistance in vivo: advantages, limitations, and appropriate usage.
[17957034] Am J Physiol Endocrinol Metab 294(1): E15-26 (2008)

Glucocorticoids produce whole body insulin resistance with changes in cardiac metabolism.
[17077342] Am J Physiol Endocrinol Metab 292(3): E654-67 (2007)

Role of mitochondrial dysfunction in insulin resistance.
[18309108] Circ Res 102(4): 401-14 (2008)

Why test the children?: Understanding insulin resistance, its complications, and its progression.
[12453984] Diabetes Care 25(12): 2350-1 (2002)

How to measure hepatic insulin resistance?
[19195628] Diabetes Metab 34(6 Pt 2): 664-73 (2008)

Mitochondrial energetics and insulin resistance.
[18202132] Endocrinology 149(3): 950-4 (2008)

Insulin resistance and steatosis in hepatitis C virus infection.
[15951532] Gut 54(7): 903-6 (2005)

Insulin sensitivity and its measurement: structural commonalities among the methods.
[11134088] J Clin Endocrinol Metab 85(12): 4426-33 (2000)

Clinical review 97: Syndromes of severe insulin resistance.
[9745395] J Clin Endocrinol Metab 83(9): 3025-30 (1998)

Insulin sensitivity: modulation by nutrients and inflammation.
[18769626] J Clin Invest 118(9): 2992-3002 (2008)

Molecular mechanisms of insulin resistance in chronic hepatitis C.
[19764085] World J Gastroenterol 15(35): 4356-64 (2009)

Insulin resistance: a metabolic pathway to chronic liver disease.
[16250043] Hepatology 42(5): 987-1000 (2005)

RNAi screens reveal novel metabolic regulators: RIP140, MAP4k4 and the lipid droplet associated fat specific protein (FSP) 27.
[18171433] Acta Physiol (Oxf) 192(1): 103-15 (2008)

Etiology of insulin resistance.
[16563942] Am J Med 119(5 Suppl 1): S10-6 (2006)

Adiponectin in insulin resistance: lessons from translational research.
[19906806] Am J Clin Nutr 91(1): 258S-261S (2010)

Postburn trauma insulin resistance and fat metabolism.
[17957035] Am J Physiol Endocrinol Metab 294(1): E1-9 (2008)

Renin-angiotensin-aldosterone system and oxidative stress in cardiovascular insulin resistance.
[17586614] Am J Physiol Heart Circ Physiol 293(4): H2009-23 (2007)

Acyl-CoA synthesis, lipid metabolism and lipotoxicity.
[19818872] Biochim Biophys Acta 1801(3): 246-51 (2010)

Lipid oversupply, selective insulin resistance, and lipotoxicity: molecular mechanisms.
[19796706] Biochim Biophys Acta 1801(3): 252-65 (2010)

Inflammation in obesity is the common link between defects in fatty acid metabolism and insulin resistance.
[17438370] Cell Cycle 6(8): 888-94 (2007)

Pathophysiology of insulin resistance and steatosis in patients with chronic viral hepatitis.
[22039318] World J Gastroenterol 17(36): 4055-62 (2011)

Importance of hepatitis C virus-associated insulin resistance: therapeutic strategies for insulin sensitization.
[20419831] World J Gastroenterol 16(16): 1943-52 (2010)

Unraveling the cellular mechanism of insulin resistance in humans: new insights from magnetic resonance spectroscopy.
[15304632] Physiology (Bethesda) 19(-): 183-90 (2004)

Microvascular dysfunction in obesity: a potential mechanism in the pathogenesis of obesity-associated insulin resistance and hypertension.
[17699878] Physiology (Bethesda) 22(-): 252-60 (2007)

Mechanistic insights into diuretic-induced insulin resistance.
[18981323] Hypertension 52(6): 1009-11 (2008)

Thiazide diuretics alone or with beta-blockers impair glucose metabolism in hypertensive patients with abdominal obesity.
[19917873] Hypertension 55(1): 15-7 (2010)

Mechanisms of insulin resistance in humans and possible links with inflammation.
[15824195] Hypertension 45(5): 828-33 (2005)

The impact of macrophage insulin resistance on advanced atherosclerotic plaque progression.
[20056946] Circ Res 106(1): 58-67 (2010)

Innate immune pathway links obesity to insulin resistance.
[17556663] Circ Res 100(11): 1531-3 (2007)

The macrophage at the crossroads of insulin resistance and atherosclerosis.
[17556668] Circ Res 100(11): 1546-55 (2007)

Pathogenesis of insulin resistance in skeletal muscle.
[20445742] J Biomed Biotechnol 2010(-): 476279 (2010)

Skeletal muscle insulin resistance in endocrine disease.
[20300436] J Biomed Biotechnol 2010(-): 527850 (2010)

Hepatic triacylglycerol accumulation and insulin resistance.
[18997164] J Lipid Res 50 Suppl(-): S74-9 (2009)

Protein-tyrosine phosphatases: emerging targets for therapeutic intervention in type 2 diabetes and related states of insulin resistance.
[12050202] J Clin Endocrinol Metab 87(6): 2474-80 (2002)

Limitations in surrogate measures of insulin resistance.
[21051585] J Clin Endocrinol Metab 95(11): 4874-6 (2010)

Insulin resistance syndrome in children.
[15181020] J Clin Endocrinol Metab 89(6): 2526-39 (2004)

Hypoadiponectinemia--cause or consequence of human "insulin resistance"?
[20164291] J Clin Endocrinol Metab 95(4): 1544-54 (2010)

Does insulin resistance need resistin?
[17554055] J Clin Endocrinol Metab 92(6): 2036-7 (2007)

An integrated view of insulin resistance and endothelial dysfunction.
[18775359] Endocrinol Metab Clin North Am 37(3): 685-711, ix-x (2008)

IGF-I treatment of insulin resistance.
[17785698] Eur J Endocrinol 157 Suppl 1(-): S51-6 (2007)

The role of mitochondria in the pathophysiology of skeletal muscle insulin resistance.
[19861693] Endocr Rev 31(1): 25-51 (2010)

Cardiovascular actions of insulin.
[17525361] Endocr Rev 28(5): 463-91 (2007)

Evidence-based and potential benefits of metformin in the polycystic ovary syndrome: a comprehensive review.
[19056992] Endocr Rev 30(1): 1-50 (2009)

Mouse models of insulin resistance.
[15044684] Physiol Rev 84(2): 623-47 (2004)

Disordered lipid metabolism and the pathogenesis of insulin resistance.
[17429039] Physiol Rev 87(2): 507-20 (2007)

Inflammation and insulin resistance.
[18053812] FEBS Lett 582(1): 97-105 (2008)

Lipocalins and insulin resistance: etiological role of retinol-binding protein 4 and lipocalin-2?
[17202496] Clin Chem 53(1): 5-7 (2007)

Tissue-specific insulin resistance.
[15299149] Postgrad Med J 80(946): 435 (2004)

Insulin resistance in chronic hepatitis C: mechanisms and clinical relevance.
[20047129] Swiss Med Wkly 139(47-48): 678-84 (2009)

Antioxidants: do they have a role in the treatment of insulin resistance?
[17496361] Indian J Med Res 125(3): 355-72 (2007)

Hexosamine flux, the O-GlcNAc modification, and the development of insulin resistance in adipocytes.
[19799964] Mol Cell Endocrinol 318(1-2): 44-53 (2010)

Obesity-induced insulin resistance and hyperglycemia: etiologic factors and molecular mechanisms.
[18580184] Anesthesiology 109(1): 137-48 (2008)

Inflammatory mediators and insulin resistance in obesity: role of nuclear receptor signaling in macrophages.
[20508742] Mediators Inflamm 2010(-): 219583 (2010)

Mechanisms of obesity-associated insulin resistance: many choices on the menu.
[17575046] Genes Dev 21(12): 1443-55 (2007)

Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes.
[18401346] Nat Rev Mol Cell Biol 9(5): 367-77 (2008)

D-chiro-inositol glycans in insulin signaling and insulin resistance.
[20811656] Mol Med 16(11-12): 543-52 (2010)

Inflammatory mechanisms in the regulation of insulin resistance.
[18235842] Mol Med 14(3-4): 222-31 (2008)

Adiponectin and its role in the obesity-induced insulin resistance and related complications.
[15046547] Physiol Res 53(2): 123-9 (2004)

Insulin resistance concepts.
[17468377] Diabetes Care 30(5): 1320-6 (2007)

Adipocytokines and insulin resistance: the possible role of lipocalin-2, retinol binding protein-4, and adiponectin.
[19875582] Diabetes Care 32 Suppl 2(-): S362-7 (2009)

Where does insulin resistance start? The brain.
[19875547] Diabetes Care 32 Suppl 2(-): S174-7 (2009)

Viewpoints on the way to the consensus session: where does insulin resistance start? The adipose tissue.
[19875546] Diabetes Care 32 Suppl 2(-): S168-73 (2009)

Viewpoints on the way to a consensus session: where does insulin resistance start? The liver.
[19875545] Diabetes Care 32 Suppl 2(-): S164-7 (2009)

Skeletal muscle insulin resistance is the primary defect in type 2 diabetes.
[19875544] Diabetes Care 32 Suppl 2(-): S157-63 (2009)

Third Annual World Congress on the Insulin Resistance Syndrome: mediators, antecedents, and measurement.
[16801606] Diabetes Care 29(7): 1700-6 (2006)

cJun NH2-terminal kinase 1 (JNK1): roles in metabolic regulation of insulin resistance.
[20452774] Trends Biochem Sci 35(9): 490-6 (2010)

Molecular mechanism of insulin resistance and obesity.
[14610248] Exp Biol Med (Maywood) 228(10): 1111-7 (2003)

Insulin resistance induced by physical inactivity is associated with multiple transcriptional changes in skeletal muscle in young men.
[20739510] Am J Physiol Endocrinol Metab 299(5): E752-63 (2010)

Inhibition of hepatic Niemann-Pick C1-like 1 improves hepatic insulin resistance.
[19654286] Am J Physiol Endocrinol Metab 297(5): E1030-8 (2009)

Autophagy: roles in obesity-induced ER stress and adiponectin downregulation in adipocytes.
[20864818] Autophagy 6(8): 1196-7 (2010)

Repression of GLUT4 expression by the endoplasmic reticulum stress response in 3T3-L1 adipocytes.
[17698029] Biochem Biophys Res Commun 362(1): 188-92 (2007)

Defective hepatic autophagy in obesity promotes ER stress and causes insulin resistance.
[20519119] Cell Metab 11(6): 467-78 (2010)

Oxidative stress biology and cell injury during type 1 and type 2 diabetes mellitus.
[17311546] Curr Neurovasc Res 4(1): 63-71 (2007)

Obesity, insulin resistance and free fatty acids.
[21297467] Curr Opin Endocrinol Diabetes Obes 18(2): 139-43 (2011)

Sodium phenylbutyrate, a drug with known capacity to reduce endoplasmic reticulum stress, partially alleviates lipid-induced insulin resistance and beta-cell dysfunction in humans.
[21270237] Diabetes 60(3): 918-24 (2011)

Tauroursodeoxycholic Acid may improve liver and muscle but not adipose tissue insulin sensitivity in obese men and women.
[20522594] Diabetes 59(8): 1899-905 (2010)

An inflammatory cascade leading to hyperresistinemia in humans.
[15578112] PLoS Med 1(2): e45 (2004)

Hepatitis C virus infection: molecular pathways to insulin resistance.
[22008087] Virol J 8(-): 474 (2011)

Acute insulin resistance following injury.
[19800814] Trends Endocrinol Metab 20(9): 429-35 (2009)

Fetal origins of insulin resistance and the metabolic syndrome: a key role for adipose tissue?
[19815442] Diabetes Metab 36(1): 11-20 (2010)

Insulin resistance and steatosis in humans.
[19195626] Diabetes Metab 34(6 Pt 2): 649-57 (2008)

Is skeletal muscle mitochondrial dysfunction a cause or an indirect consequence of insulin resistance in humans?
[19349201] Diabetes Metab 35(3): 159-67 (2009)

Role of macrophage tissue infiltration in obesity and insulin resistance.
[19539513] Diabetes Metab 35(4): 251-60 (2009)

Adipokines: the missing link between insulin resistance and obesity.
[18093861] Diabetes Metab 34(1): 2-11 (2008)

New insights into the pathogenesis of insulin resistance in humans using magnetic resonance spectroscopy.
[16642961] Obesity (Silver Spring) 14 Suppl 1(-): 34S-40S (2006)

Narrative review: the emerging clinical implications of the role of aldosterone in the metabolic syndrome and resistant hypertension.
[19487712] Ann Intern Med 150(11): 776-83 (2009)

Molecular mechanisms of insulin resistance that impact cardiovascular biology.
[15504952] Diabetes 53(11): 2735-40 (2004)

Are oxidative stress-activated signaling pathways mediators of insulin resistance and beta-cell dysfunction?
[12502486] Diabetes 52(1): 1-8 (2003)

Diabetes and suppressors of cytokine signaling proteins.
[17259405] Diabetes 56(2): 541-8 (2007)

Molecular mechanisms of insulin resistance: serine phosphorylation of insulin receptor substrate-1 and increased expression of p85alpha: the two sides of a coin.
[16873706] Diabetes 55(8): 2392-7 (2006)

Insulin resistance as a membrane microdomain disorder.
[17409686] Yakugaku Zasshi 127(4): 579-86 (2007)

Lipid-induced insulin resistance: unravelling the mechanism.
[20609972] Lancet 375(9733): 2267-77 (2010)

Skeletal muscle insulin resistance: roles of fatty acid metabolism and exercise.
[18801860] Phys Ther 88(11): 1279-96 (2008)

Insulin resistance and chronic liver disease.
[21731901] World J Hepatol 3(5): 99-107 (2011)

Molecular mechanisms of insulin resistance in type 2 diabetes mellitus.
[21537430] World J Diabetes 1(3): 68-75 (2010)

Surrogate markers of insulin resistance: A review.
[21537426] World J Diabetes 1(2): 36-47 (2010)

Molecular mechanism of insulin resistance in obesity and type 2 diabetes.
[20526383] Korean J Intern Med 25(2): 119-29 (2010)

The vascular actions of insulin control its delivery to muscle and regulate the rate-limiting step in skeletal muscle insulin action.
[19283361] Diabetologia 52(5): 752-64 (2009)

D-chiro-inositol--its functional role in insulin action and its deficit in insulin resistance.
[11900279] Int J Exp Diabetes Res 3(1): 47-60 (2002)

Skeletal muscle insulin resistance: the interplay of local lipid excess and mitochondrial dysfunction.
[19766267] Metabolism 59(1): 70-85 (2010)

Uncoupling proteins: role in insulin resistance and insulin insufficiency.
[18220632] Curr Diabetes Rev 2(3): 271-83 (2006)

Protein kinase C isoforms: mediators of reactive lipid metabolites in the development of insulin resistance.
[21176778] FEBS Lett 585(2): 269-74 (2011)

Defects in TLR3 expression and RNase L activation lead to decreased MnSOD expression and insulin resistance in muscle cells of obese people.
[24651439] Cell Death Dis 5():e1136 (2014)

Hypoadiponectinemia in obesity: association with insulin resistance.
[24426202] Indian J Clin Biochem 28(2):158-63 (2013)

Serum adipocyte fatty acid-binding protein in the critically ill.
[23463959] Crit Care 17(2):121 (2013)

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